Drug Interactions

Tell your doctor or pharmacist if you are taking or if you are planning to take any over-the-counter or prescription medications or dietary supplements with gastrointestinal anticholinergics or antispasmodics. Doses of one or both drugs may need to be modified or a different drug may need to be prescribed. The following drugs and drug classes interact with gastrointestinal anticholinergics or antispasmodics.

Amantadine (eg, Symmetrel)

MAO Inhibitors (eg, Phenelzine)

Antacids (eg, Maalox)

Meperidine (eg, Demerol)

Anticholinergics, other (eg, bella donna alkaloids)

Metoclopramide (eg, Reglan)

Nitrates (eg, Nitroglycerin)

Benzodiazepines (eg, Diazepam)

Phenothiazines (eg, Promethazine)

Beta Blockers (eg, Atenolol)

Side Effects

Every drug is capable of producing side effects. Many anticholinergic or antispasmodic users experience no, or minor, side effects. The frequency and severity of side effects depend on many factors including dose, duration of therapy and individual susceptibility. Possible side effects include:

Digestive Tract: Nausea; vomiting; bloating; constipation; abdominal pain; appetite loss; difficulty swallowing.

Nervous System: Confusion; excitement; restlessness; hallucinations; headache; nervousness; drowsiness; dizziness; lightheadedness; tingling; numbness; difficulty moving; fainting; disorientation; short-term memory loss; slurred speech; incoordination; coma; exaggerated sense of well-being; decreased anxiety; tiredness; speech disturbance; weak­ness; sleeplessness; fever; tremor.

Circulatory System: Pounding in the chest (palpitations); fast or irregular heartbeat.

Respiratory System: Difficulty breathing; nasal stuffiness; nasal congestion.

Skin: Rash; itching; flushing; decreased sweating; hives; skin disorder.

Other: Difficult urination; muscle weakness; visual problems; blurred vision; dry mouth; taste changes; urinary retention; impotence; reduced breast milk production and flow; enlarged pupils; eye sensitivity to light; increased eye pressure.

Guidelines for Use

Take exactly as prescribed.

Take 30 minutes before meals. Take mepenzolate with meals and at bedtime.

If a dose is missed, take it as soon as possible. If several hours have passed or if it is nearing time for the next dose, do not double the dose to “catch up” (unless advised by your doctor). If more than one dose is missed or it is necessary to establish a new dosage schedule, contact your doctor or pharmacist.

May cause drowsiness, dizziness or blurred vision. Use caution when driving or performing other tasks requiring mental alertness, coordination or physical dexterity.

Notify your doctor if skin rash, flushing, rapid heartbeat, urinary retention, blurred vision or eye problems occur.

May cause dry mouth, difficulty in urination or constipation, or increased sensitivity to light. Notify your doctor if these effects persist or bec.ome severe.

If symptoms of fever, heatstroke and decreased sweating occur,discontinue the drug and contact a doctor immediately.

Signs of overdosage with these drugs include. Headache,nausea, vomiting, dizziness, dry mouth, blurred vision, rapid heartbeat rhythm, dry skin, fever, difficulty in swallowing, excitation tiredness stupor, coma, respiratory depression and paralysis doctor if these instances occur.

Avoid alcohol and medicines (eg, tranquilizers, that cause drowsiness.

Sucking on hard sugarless candy, drinking fluids and oral hygiene can relieve dry mouth.

Inform your doctor if you are pregnant, become to become pregnant or are breastfeeding.

Store at room temperature.

New Diet Drug, Alli-May Have Explosive Results

On February 7, 2007, GlaxoSmithKline PLC received FDA approval to begin selling an over-the-counter diet drug called Alli. This drug is a new version of orlistat – similar to the prescription drug, Xenical, that is already on the market.

Alli will be a 60-milligram capsule which is about half the strength of the prescription version. It is expected to be available sometime this summer at a cost of about $1 – $2 a day.

It will be the only FDA-approved weight-loss product available over the counter.

**How It Works**

Alli is only for people 18 years of age and older. By itself, the drug is not expected to be that effective. It should be used in conjunction with a reduced-calorie, low-fat diet and an exercise program.

One capsule should be taken before every meal that contains fat. Alli works by blocking the absorption of some of that dietary fat in the gastrointestinal tract.

Six-month clinical trials of the drug showed that obese people lost approximately one more pound a month. Not a week, a month. In my opinion, that’s a minor benefit.

** The Potentially Disgusting Side Effects**

Gastrointestinal side effects are believed to be common with orlistat. These may include fecal urgency or incontinence, explosive diarrhea, anal leakage, increased number of bowel movements, abdominal cramping and oily discharge.

Depending on how severe these gastrointestinal side effects may be (if you experience them at all), you may need to wear adult diapers or you could end up with soiled undies.

The smell would probably be unpleasant as well, especially if Alli shares Xenical’s potential side effect of gas with fecal discharge.

For an extra pound a month, I wouldn’t want to suffer those gastrointestinal side effects. It sounds messy, stinky, and potentially humiliating if you can’t control your bowel movements in public.

If you start experiencing these side effects, you’d better not be too far from a bathroom.

**If That’s Not Bad Enough For You, There’s More**

Along with dietary fat, Alli may decrease the absorption of some fat-soluble vitamins (A, D, E and K) and beta-carotene. We need these nutrients to keep us healthy.

For example, Vitamin E may help your heart or prevent blood clots. Vitamin K may help your blood to clot normally.

You may need to take a daily multivitamin to counteract these effects. But you should see your doctor for specific medical advice.

There are other potential side effects as well.

For example, I believe that diabetics, people on immunosuppressant or blood-thinning drugs, or patients with thyroid disease are not supposed to take orlistat.

But again, you should check with your doctor to be sure that this drug is safe for you.

**Is It Worth It?**

Is losing an extra pound a month really worth the risk of these potential side effects? Couldn’t the same results be achieved through diet and exercise alone?

And how do people feel who experience these side effects? Apart from inconvenience and possible humiliation, wouldn’t you feel sick from the gastro effects? I thought the point of weight loss was to feel better.

Or is this just a way of preying on the desperation of obese people? And making a lot of money in the process?

Important Disclaimer: This information is presented for educational purposes only. This isn’t medical advice and it’s not a substitute for any advice or treatment from your physician. You should always see your doctor before taking any new medication or starting any new weight loss regimen.

Copyright (c) 2007 Debbie Fontana

Arthritis Pain Medication – Instead of Drugs, Fight Arthritis the All-Natural Way

Are you taking arthritis pain medicine? Well there is a better way to get well without drugs. Did you know aspirin and other over-the-counter drugs can put you in the hospital or under the ground? Every doctor who was awake during medical classes in college knows the dangers of NSAIDs (non-steroidal anti-inflammatory drugs).

They know for example, that aspirin causes the lining of the stomach to bleed and that it burns tiny holes into your gastrointestinal tract. You may lose up to one teaspoon of blood each time you take a standard dose of aspirin (more if you are at risk for bleeding or consume more than the standard dose). Sadly, the reality is that NSAIDs do more than just cause gastrointestinal problems. They kill over 10,000 people a year and are the cause of over 76,000 hospitalizations annually.

And of course you remember the pain killers Vioxx and Celebrex. We learned what many doctors already knew, that Vioxx and Celebrex could lead to heart attacks and strokes. Yet millions of arthritis and pain sufferers were prescribed these dangerous drugs so that they could have a normal life.

However, a normal life can be had without these dangerous medications. There are several natural ways to fight arthritis joint pain. The fact is you can see a reduction in the pain and inflammation you are suffering by simply making a few key changes to your overall lifestyle.

Eat Healthy

One of the best things to do now is to change your diet. The foods you eat are what the body has to derive nutrients from. If you do not eat a full, antioxidant rich diet, your body is not able to reduce the inflammation happening in your joints. This will lead to pain and worsening of the arthritis. You need to start eating alkaline-forming foods. Scientific research shows that by doing so you can bullet-proof your body against disease-including arthritis.

Lose Weight

Controlling your weight can have a tremendous effect on pain and inflammation. If you are overweight it increases the amount of pressure that is on your joints. By losing weight you give the body a better chance at improving its overall ability to fight off the inflammation. For many, this alone is the best way to reduce the pain.


Staying hydrated is very important for any of the above items to work. Water keeps the cells hydrated and keeps the cells clean by flushing out toxins. It is necessary to drink water before you feel thirsty since thirst is actually the first sign of dehydration.

Natural Cure For Arthritis — A 7 Day Miracle That Stops It Dead Its Tracks

This is just the tip of the iceberg. If you really want a step-by-step guide to cure arthritis including osteoarthritis, RA, and gout, download my special report. Learn why I kick milk to the curb and what the medical establishment doesn’t want you to know about curing your arthritis with simple ingredients found in your kitchen cupboard. Fact is, you will learn why everything you thought you knew about this disease was wrong. And discover how to end your pain and suffering forever.